Alea.cuBase allows to create GPU accelerated applications at all levels of sophistication, from simple GPU kernels up to complex GPU algorithms using textures, shared memory and other advanced GPU programming techniques, fully integrated into .NET. The GPU kernels are developed in functional language F# and are callable from any other .NET language. No additional wrappers or assembly translation processes are required. Alea.cuBase allows dynamic creation of GPU code at run time, thereby opening completely new dimensions for GPU accelerated applications. Trial versions are available at http://www.quantalea.net/products.